头部和颈部鳞状细胞癌（HNSCC）的病因涉及多种致癌物，例如酒精，烟草和人乳头瘤病毒（HPV）。由于HPV感染会影响HNSCC患者的预后，治疗和存活，因此确定这些肿瘤的HPV状态很重要。在本文中，我们提出了一个新颖的三胞胎级损耗函数和HPV状态预测的多个实例学习管道。这仅使用两个HNSCC同类群体上的常规H＆E染色WSI，在HPV检测中实现了新的最新性能。此外，还进行了全面的肿瘤微环境分析，从基因组，免​​疫学和细胞角度来看，HPV +/- HNSCC之间的独特模式。鉴定了与巨噬细胞和结缔细胞（例如成纤维细胞）（例如，成纤维细胞）（例如，成纤维细胞）与T细胞不同亚型（例如T细胞，CD8+ T细胞）的正类型的正相关性，这与临床发现一致。还针对HPV感染状态鉴定了独特的基因表达谱，并且与现有发现一致。

计算病理（CPATH）是一种具有关于组织病理研究的新兴领域，通过计算和分析组织载玻片的数字化高分辨率图像的处理算法。CPATH最近的深度学习的发展已经成功地利用了组织学图像中的原始像素数据的纯粹体积，以预测诊断域，预测，治疗敏感性和患者分层中的目标参数 - 覆盖新数据驱动的AI时代的承诺既组织病理学和肿瘤。使用作为燃料和作为发动机的燃料和AI的数据，CPATH算法准备好用于起飞和最终发射到临床和药物轨道中。在本文中，我们讨论了CPATH限制和相关挑战，使读者能够区分HIPE的希望，并为未来的研究提供指示，以克服这个崭露头角领域的一些主要挑战，以使其发射到两个轨道上。

This paper presents our solutions for the MediaEval 2022 task on DisasterMM. The task is composed of two subtasks, namely (i) Relevance Classification of Twitter Posts (RCTP), and (ii) Location Extraction from Twitter Texts (LETT). The RCTP subtask aims at differentiating flood-related and non-relevant social posts while LETT is a Named Entity Recognition (NER) task and aims at the extraction of location information from the text. For RCTP, we proposed four different solutions based on BERT, RoBERTa, Distil BERT, and ALBERT obtaining an F1-score of 0.7934, 0.7970, 0.7613, and 0.7924, respectively. For LETT, we used three models namely BERT, RoBERTa, and Distil BERTA obtaining an F1-score of 0.6256, 0.6744, and 0.6723, respectively.

Conventional cameras capture image irradiance on a sensor and convert it to RGB images using an image signal processor (ISP). The images can then be used for photography or visual computing tasks in a variety of applications, such as public safety surveillance and autonomous driving. One can argue that since RAW images contain all the captured information, the conversion of RAW to RGB using an ISP is not necessary for visual computing. In this paper, we propose a novel $\rho$-Vision framework to perform high-level semantic understanding and low-level compression using RAW images without the ISP subsystem used for decades. Considering the scarcity of available RAW image datasets, we first develop an unpaired CycleR2R network based on unsupervised CycleGAN to train modular unrolled ISP and inverse ISP (invISP) models using unpaired RAW and RGB images. We can then flexibly generate simulated RAW images (simRAW) using any existing RGB image dataset and finetune different models originally trained for the RGB domain to process real-world camera RAW images. We demonstrate object detection and image compression capabilities in RAW-domain using RAW-domain YOLOv3 and RAW image compressor (RIC) on snapshots from various cameras. Quantitative results reveal that RAW-domain task inference provides better detection accuracy and compression compared to RGB-domain processing. Furthermore, the proposed \r{ho}-Vision generalizes across various camera sensors and different task-specific models. Additional advantages of the proposed $\rho$-Vision that eliminates the ISP are the potential reductions in computations and processing times.

Technology has transformed traditional educational systems around the globe; integrating digital learning tools into classrooms offers students better opportunities to learn efficiently and allows the teacher to transfer knowledge more easily. In recent years, there have been many improvements in smart classrooms. For instance, the integration of facial emotion recognition systems (FER) has transformed the classroom into an emotionally aware area using the power of machine intelligence and IoT. This paper provides a consolidated survey of the state-of-the-art in the concept of smart classrooms and presents how the application of FER systems significantly takes this concept to the next level

Deep learning models require an enormous amount of data for training. However, recently there is a shift in machine learning from model-centric to data-centric approaches. In data-centric approaches, the focus is to refine and improve the quality of the data to improve the learning performance of the models rather than redesigning model architectures. In this paper, we propose CLIP i.e., Curriculum Learning with Iterative data Pruning. CLIP combines two data-centric approaches i.e., curriculum learning and dataset pruning to improve the model learning accuracy and convergence speed. The proposed scheme applies loss-aware dataset pruning to iteratively remove the least significant samples and progressively reduces the size of the effective dataset in the curriculum learning training. Extensive experiments performed on crowd density estimation models validate the notion behind combining the two approaches by reducing the convergence time and improving generalization. To our knowledge, the idea of data pruning as an embedded process in curriculum learning is novel.

Density estimation is one of the most widely used methods for crowd counting in which a deep learning model learns from head-annotated crowd images to estimate crowd density in unseen images. Typically, the learning performance of the model is highly impacted by the accuracy of the annotations and inaccurate annotations may lead to localization and counting errors during prediction. A significant amount of works exist on crowd counting using perfectly labelled datasets but none of these explore the impact of annotation errors on the model accuracy. In this paper, we investigate the impact of imperfect labels (both noisy and missing labels) on crowd counting accuracy. We propose a system that automatically generates imperfect labels using a deep learning model (called annotator) which are then used to train a new crowd counting model (target model). Our analysis on two crowd counting models and two benchmark datasets shows that the proposed scheme achieves accuracy closer to that of the model trained with perfect labels showing the robustness of crowd models to annotation errors.

The rapid outbreak of COVID-19 pandemic invoked scientists and researchers to prepare the world for future disasters. During the pandemic, global authorities on healthcare urged the importance of disinfection of objects and surfaces. To implement efficient and safe disinfection services during the pandemic, robots have been utilized for indoor assets. In this paper, we envision the use of drones for disinfection of outdoor assets in hospitals and other facilities. Such heterogeneous assets may have different service demands (e.g., service time, quantity of the disinfectant material etc.), whereas drones have typically limited capacity (i.e., travel time, disinfectant carrying capacity). To serve all the facility assets in an efficient manner, the drone to assets allocation and drone travel routes must be optimized. In this paper, we formulate the capacitated vehicle routing problem (CVRP) to find optimal route for each drone such that the total service time is minimized, while simultaneously the drones meet the demands of each asset allocated to it. The problem is solved using mixed integer programming (MIP). As CVRP is an NP-hard problem, we propose a lightweight heuristic to achieve sub-optimal performance while reducing the time complexity in solving the problem involving a large number of assets.

The increase in the number of unmanned aerial vehicles a.k.a. drones pose several threats to public privacy, critical infrastructure and cyber security. Hence, detecting unauthorized drones is a significant problem which received attention in the last few years. In this paper, we present our experimental work on three drone detection methods (i.e., acoustic detection, radio frequency (RF) detection, and visual detection) to evaluate their efficacy in both indoor and outdoor environments. Owing to the limitations of these schemes, we present a novel encryption-based drone detection scheme that uses a two-stage verification of the drone's received signal strength indicator (RSSI) and the encryption key generated from the drone's position coordinates to reliably detect an unauthorized drone in the presence of authorized drones.

The compute-intensive nature of neural networks (NNs) limits their deployment in resource-constrained environments such as cell phones, drones, autonomous robots, etc. Hence, developing robust sparse models fit for safety-critical applications has been an issue of longstanding interest. Though adversarial training with model sparsification has been combined to attain the goal, conventional adversarial training approaches provide no formal guarantee that the models would be robust against any rogue samples in a restricted space around a benign sample. Recently proposed verified local robustness techniques provide such a guarantee. This is the first paper that combines the ideas from verified local robustness and dynamic sparse training to develop `SparseVLR'-- a novel framework to search verified locally robust sparse networks. Obtained sparse models exhibit accuracy and robustness comparable to their dense counterparts at sparsity as high as 99%. Furthermore, unlike most conventional sparsification techniques, SparseVLR does not require a pre-trained dense model, reducing the training time by 50%. We exhaustively investigated SparseVLR's efficacy and generalizability by evaluating various benchmark and application-specific datasets across several models.